What happens to TSH when we remove the Thyroid Gland?
Ya for example an experiment animal, we remove the thyroid gland. My "theory" is that, if TRH is produced from Hypothalamus and it makes the Hypofize (sorry if I spelled wrong in my language) produce TSH, that make Thyroid produce T3 and T4, but T3 and T4 influence in increase or decrease of TRH, then if we remove thyroid, the levels of TRH should be decreased until stopped. Which is the right answer?
The question I think you’re asking is about TSH rather than TRH, right? TSH is the one we mainly look at (over T3 and T4 in screening, especially). If the thyroid gland is removed (whether surgically or through radioactive iodine ablation), and this is usually done because a person is hyperthyroid to the point that methimazole isn’t working to relieve the hyperthyroidism, then the TSH will go UP. A high TSH, as we know, indicates a hypothyroid state.